The Transnational Boxing Rankings Board's latest rankings- those based on fights held through September 25, 2021- were posted on the TBRB's website September 27, 2021. There were changes to the rankings of the heavyweight, cruiserweight, light heavyweight, super middleweight, featherweight, and junior flyweight divisions and to the Pound For Pound Top Ten.

HEAVYWEIGHT:

Champion: Tyson Fury

1 (10) Oleksandr Usyk
2 (1) Anthony Joshua
3 (2) Deontay Wilder
4 (3) Dillian Whyte
5 (4) Andy Ruiz, Jr.
6 (5) Joe Joyce
7 (6) Luis Ortiz
8 (7) Michael Hunter
9 (8) Joseph Parker
10 (9) Otto Wallin

Out from rankings posted September 20, 2021:
No one

CRUISERWEIGHT:

Champion: Mairis Briedis

1 (3) Lawrence Okolie
2 (1) Yuniel Dorticos
3 (2) Ilunga Makabu
4 (4) Thabiso Mchunu
5 (5) Kevin Lerena
6 (6) Aleksei Papin
7 (7) Michal Cieslak
8 (8) Mateusz Masternak
9 (9) Brandon Glanton
10 (10) Efetobor Apochi

Out from rankings posted September 20, 2021:
No one

LIGHT HEAVYWEIGHT:

Champion: Artur Beterbiev

1 (1) Dmitry Bivol
2 (2) Joe Smith, Jr.
3 (3) Gilberto Ramirez
4 (4) Maxim Vlasov
5 (5) Marcus Browne
6 (6) Badou Jack
7 (7) Eleider Alvarez
8 (8) Joshua Buatsi
9 (9) Robin Krasniqi
10 (-) Callum Smith- had been #4 at 168

Out from rankings posted September 20, 2021:
#10 Lyndon Arthur

SUPER MIDDLEWEIGHT:

Champion: OPEN

1 (1) Saul "Canelo" Alvarez
2 (2) Caleb Plant
3 (3) David Benavidez
4 (5) John Ryder
5 (6) Danny Jacobs
6 (7) Carlos Gongora
7 (8) David Morrell, Jr.
8 (9) Billy Joe Saunders
9 (10) Fedor Chudinov
10 (-) Gabriel Rosado

Out from rankings posted September 20, 2021:
#4 Callum Smith- now ranked #10 at 175

FEATHERWEIGHT:

Champion: OPEN

1 (2) Mauricio Lara
2 (3) Kid Galahad
3 (4) Emanuel Navarrete
4 (5) Tugstsogt Nyambayar
5 (6) Jessie Magdaleno
6 (7) Josh Warrington
7 (8) Eduardo Ramirez
8 (9) Leigh Wood
9 (10) Mark Magsayo
10 (-) Michael Conlan

Out from rankings September 20, 2021:
#1 Gary Russell, Jr.- prolonged inactivity

JUNIOR FLYWEIGHT:

Champion: OPEN

1 (-) Masamichi Yabuki
2 (2) Hiroto Kyoguchi
3 (3) Felix Alvarado
4 (4) Elwin Soto
5 (1) Kenshiro Teraji
6 (5) Mark Vicelles
7 (6) Sivenathi Nontshinga
8 (8) Esteban Bermudez
9 (9) Jesse Rodriguez
10 (10) Daniel Matellon

Out from rankings posted September 20, 2021:
#7 Agustin Mauro Gauto- extended inactivity within the division

POUND FOR POUND:

1 (1) Saul Alvarez
2 (4) Oleksandr Usyk
3 (2) Naoya Inoue
4 (3) Terence Crawford
5 (5) Errol Spence, Jr.
6 (6) Josh Taylor
7 (7) Tyson Fury
8 (8) Juan Francisco Estrada
9 (9) Gennady Golovkin
10 (10) Teofimo Lopez

Out from rankings posted September 13, 2021:
No one